Cancer has become a leading cause of mortality worldwide, next only to cardiovascular diseases. Patients who develop cancer are known to exhibit several genomic alterations. Conventional therapies for the management of cancer have their own limitations. Immunotherapy is coming up as a promising new option for millions of patients who are suffering from end stage metastasis or refractory malignancies. To this end, the goal of cancer immunotherapy is to recruit and potentiate immune cells that can generate a robust and long lasting immune response and specifically target the cancer cells with minimum damage to normal cells. These treatment strategies, when used either alone or in combination, are known to significantly effect tumor growth and have even produced cures. In this brief review, some of the most popular cancer immunotherapy approaches shall be reviewed. Recent data from clinical trials suggest that combining more than one immunotherapy mechanisms, in conjunction with other treatment options like chemotherapy, radiotherapy and targeted therapy , may be the way forward to a complete cancer cure.
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