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VOLUME 1 , ISSUE 2 ( July-December, 2018 ) > List of Articles

ORIGINAL ARTICLE

Practice Changing Continuing Education: A Critical Review of Neurological Complications in Acute Pancreatitis

Niraj Kumar, Mamadur MR Shankar

Keywords : Acute pancreatitis, Metabolic encephalopathy, Pancreatic encephalopathy, Wernicke encephalopathy

Citation Information : Kumar N, Shankar MM. Practice Changing Continuing Education: A Critical Review of Neurological Complications in Acute Pancreatitis. Journal of Medical Academics 2018; 1 (2):109-110.

DOI: 10.5005/jp-journals-10070-0022

License: CC BY-NC 4.0

Published Online: 01-12-2018

Copyright Statement:  Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

This uncommon syndrome of pancreatic encephalopathy was first described in 1923. A manifestation of multiple organ dysfunction syndromes, generally occurs in the early stage of severe acute pancreatitis and carries high mortality of up to 57% and more. The syndrome must be distinguished from Wernicke encephalopathy, which may follow as a part of neurological complications in the last or recovery phase of acute pancreatitis, and occurs as a result of long fasting, hyperemesis and total parenteral nutrition without thiamine. Poorly recognized by clinicians, a large dose of vitamin B1 is effective in the management of Wernicke encephalopathy. In view of above the present review draws attention to the challenging and lesser recognized complications of acute pancreatitis and briefly dwells on their pathogenesis and management.


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